Sunday, July 14, 2013

Blue Jeans at Microsoft Worldwide Partner Conference

We're having an awesome time here at the Microsoft Worldwide Partner Conference (WPC) in Houston.? The weather is quite warm but the team is staying cool at Booth 1605. Stop by to learn how you can enhance video collaboration in your organization by extending Microsoft Lync?s capabilities through Blue Jeans.

Curious? Download this Wainhouse white paper to find out more and visit Booth 1605 to see a live demo!

Tweet us @BlueJeansNet and let us know how you?re enjoying the show and use #WPC13.?

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Source: http://bluejeans.com/blog/blue-jeans-microsoft-worldwide-partner-conference

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Saturday, July 13, 2013

Pacific Rim

Rinko Kikuchi in Pacific Rim.

Rinko Kikuchi in the monsters vs. robots saga Pacific Rim.

Courtesy of Warner Bros.

After you?ve seen?Pacific Rim, come back and listen to our?Spoiler?Special:

I?m not sure how to justify my sense that Guillermo Del Toro?s Pacific Rim is a cut above your average summer blockbuster in which monsters and giant robots cause major damage to iconic city skylines against a post-apocalyptic landscape. This 132-minute movie certainly has its share of long, hard-to-follow battle sequences, thinly developed human characters, and grating comic relief. Yet somehow coming out of Pacific Rim I felt energized rather than enervated, excited to describe certain nifty details of the film?s wacked-out imaginary world to friends, maybe even ready to ? sit through certain parts again?

Pacific Rim is unashamedly a film for little kids?at times it feels almost like a very well-made ?look at my toys? YouTube video by a little kid, albeit one with a staggering collection of action figures. But where the Transformers franchise has the soul-deadening effect of an extended toy infomercial, Pacific Rim offers at least some sense of watching an imagination at play. It?s based on an original story by Del Toro?s co-screenwriter Travis Beacham?original not just in the sense that it isn?t based on any pre-existing movie, comic book, TV show, or line of toys, but in the sense that it?s sort of weird. In this movie?s near future, the Earth has been attacked by creatures known as the Kaiju (the word in Japanese means ?strange beast,? and is also the name of the genre of giant-monster movies launched by 1954?s Godzilla). The Kaiju?whose rapid evolution means that they can easily appear either as serpentine sea monsters, dinosaur-like land reptiles, or insectoid flying horrors?came from deep within the Earth?s core, but also somehow through a portal to another universe located in an underwater passage called ?the Breach.? Humanity?s only defense against these invaders (other than a short-lived experiment at a peaceable ?Wall of Life,? which the monsters tear through like so much cookie dough) are gigantic fighting robots called Jaegers (German for ?hunters?). Because of their enormous size?we?re talking 25-plus stories high?Jaegers can only be operated by pairs of specially trained pilots, each in command of one-half the robot?s body, their brains locked into a state of intimate connectedness known as ?neural drift.?

All this terminology is swiftly laid out in a kind of pre-credits tutorial, in which we also learn that the voiceover provider (and nominal, if cypher-like, main character) is Raleigh Becket (Charlie Hunnam), a once-cocky Jaeger pilot who?s lost his beloved brother and co-pilot to the monsters as a result of disobeying a direct order. That?s not a wise thing to do when your commander is a legendary ex-Jaeger pilot with the glorious name of Stacker Pentecost (Idris Elba). Crushed by his brother?s death, Becket leaves piloting behind and takes a job at the ill-fated Wall of Life, but he?s coaxed back into the cockpit?or rather, the enormous robot torso?by Pentecost, whose embattled Jaeger fleet is making a last stand before it?s phased out by the UN (which in a decade or two will apparently unilaterally arbitrate all worldwide disputes?congrats in advance to whoever turns that organization around!).

To achieve the state of ?neural drift? with a co-pilot requires not only a familial sense of closeness?the teams we meet include an Australian father and son, a Russian brother and sister, and a set of Chinese triplets?but an ability to share memories and sense impressions. These inward journeys are also witnessed by the audience, in the form of trippy neural-pathway-cam montages that sometimes morph into legitimate flashbacks. I loved Del Toro?s confident shifts in between psychedelic, vaguely touchy-feely Matrix territory (?Don?t chase the rabbit! Stay in the drift. The drift is silence.?) and introspection-free monster-on-robot action, though I might have wished for a little more world-building in place of the world-destruction. The sheer scale and design of the creatures remains thrilling even when, for those not versed in the kaiju and mecha cultures that inspired the beast and ?bot designers, their sessions of whaling on each other get a little confusing and redundant. At least Del Toro mixes up the look and staging of the fight scenes?one in midair, the next (spectacularly) underwater, the next a semicomic encounter with a hungry baby Kaiju just burst from the womb?so that we never know what to expect next from these rapidly mutating world-marauders.

The human stories that take place in the interstices between Kaiju/Jaeger battles and neural-drift freak-outs are the Achilles? heel in Pacific Rim?s ingeniously designed armor. Idris Elba is effortlessly charismatic (not to mention knee-meltingly handsome) as the authoritative Pentecost, and he gets off one good laugh line when a subordinate dares to invade his well-policed personal space. But Pentecost?s longstanding paternal relationship with the young female pilot Mako Mori (Babel?s Rinko Kikuchi) is sketched far too hastily to resonate with the audience, as is Mori?s partnership-turned-romance with Hunnam?s Becket. Becket has to be one of the most unprepossessing male leads in an action movie since Ryan Reynolds in The Green Lantern. Not that it?s entirely Hunnam?s fault, given that his character description can be reduced to ?blandly attractive guy who?s sad because his brother died.? I didn?t mind Pacific Rim?s sometimes hokey dialogue, like the once-more-unto-the-breach oration in which Pentecost inspires his Jaeger team with the promise that ?Today, we are canceling the Apocalypse??it all seemed like part of the movie?s genial Saturday-afternoon-matinee vibe. But I wish those cheesy lines had been spoken by characters I?d had at least one more scene to get to know.

Opinions will be divided on the comic-relief segments featuring Charlie Day and Burn Gorman as two bumbling scientists with conflicting theories as to how to approach the study of Kaiju. Day?s character, whose obsession with procuring an intact Kaiju brain eventually gets him mixed up with black-market organ dealer Hannibal Chau (Ron Perlman), has a high-pitched voice and manic demeanor that frayed at my nerves, but I suspect the character?s broad humor and insatiable curiosity will appeal to young viewers?it?s a role Rick Moranis could have played back in the day. (Come back to the movies soon, Rick.) Perlman, a constant in Del Toro?s filmography long before his stint in the Hellboy movies, gets little to do with his enormous screen presence other than snarl at underlings while wearing steampunk goggles and gold-plated shoes (I wanted an extended Perlman-led tour of the Kaiju-organ-harvesting underworld, with all the rad props that would no doubt entail). Perlman does appear in a goofy mid-credits stinger that, refreshingly, drops nary a portentous hint at a sequel. But Pacific Rim?s ability to make monster-walloping feel fun again will no doubt make Atlantic Seaboard (or maybe Mediterranean Coastal Region) as inevitable a follow-up as the return of the Kaiju through that pesky underwater portal.

Source: http://www.slate.com/articles/arts/movies/2013/07/guillermo_del_toro_s_pacific_rim_reviewed.html

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Novel preparation method for sustained-release PLGA microspheres using water-in-oil-in-hydrophilic-oil-in-water emulsion



Original Research

(533) Total Article Views


Authors: Hong X, Wei L, Ma L, Chen Y, Liu Z, Yuan W

Published Date July 2013 Volume 2013:8 Pages 2433 - 2441

DOI: http://dx.doi.org/10.2147/IJN.S45186

Xiaoyun Hong,1,2,* Liangming Wei,3,* Liuqing Ma,2 Yinghui Chen,4 Zhenguo Liu,1 Weien Yuan2,*

1Department of Neurology, Xinhua Hospital affiliated to Shanghai JiaoTong University, School of Medicine, Shanghai, People's Republic of China; 2School of Pharmacy, Shanghai JiaoTong University, 3Key Laboratory for Thin Film and Microfabrication Technology, Ministry of Education, Research Institute of Micro/Nanometer Science and Technology, Shanghai JiaoTong University, Shanghai, People's Republic of China; 4Department of Neurology, Jinshan Hospital, Fudan University, Shanghai, People's Republic of China

*These authors contributed equally to this work

Abstract: An increasing number of drugs are needing improved formulations to optimize patient compliance because of their short half-lives in blood. Sustained-release formulations of drugs are often required for long-term efficacy, and microspheres are among the most popular ones. When drugs are encapsulated into microsphere formulations, different methods of preparation need to be used according to specific clinical requirements and the differing physicochemical characteristics of individual drugs. In this work, we developed a novel method for sustained-release drug delivery using a water-in-oil-in-hydrophilic oil-in-water (w/o/oh/w) emulsion to encapsulate a drug into poly(lactic-co-glycolic acid) (PLGA) microspheres. Different effects were achieved by varying the proportions and concentrations of hydrophilic oil and PLGA. Scanning electron and optical microscopic images showed the surfaces of the microspheres to be smooth and that their morphology was spherical. Microspheres prepared using the w/o/oh/w emulsion were able to load protein efficiently and had sustained-release properties. These results indicate that the above-mentioned method might be useful for developing sustained-release microsphere formulations in the future.

Keywords: protein, microspheres, water-in-oil-in-hydrophilic oil-in-water emulsion, sustained-release

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Source: http://dovepress.com/novel-preparation-method-for-sustained-release-plga-microspheres-using-peer-reviewed-article-IJN

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FACT CHECK: Farm bill doesn't end food stamps

WASHINGTON (AP) ? One after another, angry Democrats took to the House floor to say Republicans would increase hunger in America by stripping food stamps from the farm bill.

In reality, though, the bill passed by the House on Thursday didn't deal with food stamps at all. And the lack of congressional action on food stamps could keep the $80 billion-a-year program untouched by any cuts.

That didn't stop several Democrats from stating that the legislation "takes food nutrition from working families." House Minority Leader Nancy Pelosi told Republicans just before the bill passed on a narrow 216-208 vote: "You are taking food out of the mouths of your own poor constituents."

Money for food stamps, now called the Supplemental Nutrition Assistance Program, or SNAP, has for decades been linked to farm programs in what is known as the farm bill. That union has brought urban Democratic support for the rural farm programs, which are renewed about every five years.

But the longtime pairing ended abruptly amid battles over cuts in the food stamp program, which derailed the farm bill last month.

Some Republicans have said there is rampant fraud in the program and benefits are going to some people who aren't eligible. In the 2012 presidential campaign, then-candidate Newt Gingrich once said that people could use food stamps for anything, including trips to Hawaii. In fact, food stamps can only be used for food purchases at retail outlets. And Agriculture Department officials have cracked down on fraud in recent years.

The program has still doubled in cost since 2008, to almost $80 billion a year. Although some benefits have gone up, the main growth comes from a big jump in the number of participants, a result of the economic recession. All told, almost 47 million people used SNAP last year, or one in seven Americans. That number has not gone down this year.

Republicans said a separate food stamp bill would come at a later date. Until that happens, food stamps will continue as they are. They are paid for by annual spending bills and the Democratic Senate and President Barack Obama have strongly objected to making major cuts.

Still, the concerns that Democrats expressed Thursday could come to fruition.

House Republicans have made many different proposals that would radically overhaul food stamps ? cracking down on eligibility, increasing work requirements or adding an expiration date to the program. And after quickly moving the farm-only bill to the floor and rallying most of his caucus to vote for it, House Majority Leader Eric Cantor, R-Va., said Republicans would "act with dispatch" to get a separate food stamp bill to the floor.

But it won't be easy. Republicans themselves are divided on the issue. There is no consensus on how much the program should be cut or changed, and more moderate Republicans would likely balk at the bigger changes sought by conservatives.

Adding to the difficulty is how those issues would be resolved in conference negotiations with the Senate, which passed its own version of a farm bill in June. That bill includes food stamps and would only cut them by a half percent. Senate Democrats have said repeatedly that they will reject major changes or higher cuts to the program.

All of that disagreement strongly strengthens the possibility that current food and farm law will simply be extended when it expires in September ? keeping food stamps at the same levels they are now.

The greater concern for food stamp advocates is the long-term damage that splitting the farm bill in two, and making food stamps a partisan issue, could have. If SNAP is not protected in the farm bill, or if future farm bills don't pass, Republicans could eventually find other ways to cut SNAP ? including in the annual appropriations bills that actually fund the food stamps.

"There's a long history of bipartisanship on this," Rep. James McGovern, D-Mass., said on the floor, referring to food stamps in the farm bill. "All of a sudden this has become a partisan issue, and the target, so that you can try to balance the budget, has been placed right on the programs like SNAP."

___

Follow Mary Clare Jalonick on Twitter: http://twitter.com/mcjalonick

Source: http://news.yahoo.com/fact-check-farm-bill-doesnt-end-food-stamps-212350341.html

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Friday, July 12, 2013

Asian Markets outside Japan Rise on Bernanke's Comment

Asian markets outside Japan opened higher and rallied thereafter on US Federal Reserve Chairman Ben Bernanke's comment that US interest rates would remain low to boost economic recovery.

Hong Kong's Hang Seng was up 2.69% or 562.03 points to 21,466.59.

The Shanghai Composite index was up 4.03% or 80.83 points to 2088.95.

South Korea's Kospi was up 2.93% or 53.44 points to 1,877.60 points.

Australia's S&P/ASX was up 1.08% or 53.00 points to 4954.40

The Japanese Nikkei opened lower but inched up 0.39% or 55.98 points in afternoon trade to end at 14,472.58. Investors treaded with caution earlier in the day ahead of the Bank of Japan's (BoJ) interest rate decision. The index finished in the green after the BoJ said that the Japanese economy was "starting to recover moderately" and that exports "have been picking up."

The US Federal Reserve chief said the central bank is in no hurry to hike rates once the unemployment rate threshold of 6.5% is reached. "There will not be an automatic increase in interest rate when unemployment hits 6.5%," Bernanke said at a gathering of economists in Cambridge, Massachusetts.

Given the weakness of the US labour market, and low inflation "it may be well sometime after we hit 6.5% before rates reach any significant level".

In Japan, the central bank has left its monetary policy on hold. The BoJ, however, cut its growth and inflation forecasts from its April projections, and refrained from injecting fresh stimulus.

The news came when the Japanese stock markets were closed for lunch. The Japanese yen gained against the US dollar.

On Wall Street, indices finished largely unchanged after minutes of the two-day FOMC meeting in June failed to provide clues to the future pace of the Fed's bond-buying programme.

The Dow finished 8.68 points lower at 15,291.66. Bank of America and American Express led the pack of Dow losers. The S&P 500 inched up 0.30 points and ended at 1,652.62, while the Nasdaq closed 16.50 points higher at 3,520.76.

In Tokyo, Inpex gained 2.1% after US benchmark crude futures stayed about the $106 a barrel.

Exporters' stocks were down after the yen strengthened. Camera maker Nikon shed 3%. Electronics major Toshiba lost 2.3% while construction-equipment maker Komatsu was down 1.8%.

Electronic drive technology firm Yaskawa Electric lost about 5%, while silicon-wafers manufacturer Sumco shed 3.8%.

In Sydney, Woodside Petroleum moved up 1.3%. Gold miner Perseus Mining soared 15.5% while rival Newcrest Mining jumped 6.7% after gold futures rose for a third consecutive day.

In Hong Kong, Cnooc shot up 3.4%. Realty firm China Resources Land jumped 5.2% while rival Sun Hung Kai Properties gained 3%.

China Life Insurance moved up 4.4%. Zijin Mining gained 4% after gold futures rose for a third consecutive day.

In Shanghai, Zijin Mining gained 2%. Financial stocks fared better. Shares of Ping An Bank, Sealand Securities and Sinolink Securities shot up 10% each.

Realty firm ?Shanghai Shimao gained about 5%. Rival Poly Real Estate added 4% on news that its first-half earnings surged 35%.

In Seoul, index heavyweight Samsung Electronics jumped?3.5%. Hyundai Steel added 4.3%.

Oil refiner SK Innovation jumped 6%.

To report problems or to leave feedback about this article, e-mail:

To contact the editor, e-mail:

Source: http://au.ibtimes.com/articles/488926/20130711/nikkei-bank-japan-stocks-equities-monetary-policy.htm

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Cabinet Sports Talk - Cabinet.com

Sports

Thursday, July 11, 2013

SWIMMING

Swimmers preparing for Rotary Meet

A total of 18 swimming teams will descend on Keyes Memorial Pool from July 20-21 for the 45th Milford Rotary Swim Meet.

Milford?s local Rotary Club, the town recreation staff and the Keyes swim team volunteers are busily preparing for event that attracts nearly six hundred athletes.

Two weeks after the meet, from Aug. 3-4, Milford Recreation and the Keyes swim team will host 14 teams in the Division 2 and 4 State Championship Meet.

The Milford Rotary Chuck Wagon will be on-site at the July meet, selling Rotary hamburgers and other refreshments, with all proceeds going to help fund the annual swim meet. Commemorative T-shirts and swim accessories will also be sold as a fundraiser for the event.

SOCCER

Fall registration open

Hampshire FC/Amherst Soccer Club is now taking registrations for boys and girls ages U3-U10 for the fall Tots and Early Development programs.

No tryout required. Fall registration fee includes a week of soccer camp from Aug. 12-16 for the EDP. There are also limited spots available for the boys and girls
U11-U14 teams.

For more information ,contact Lisa Davidson at 654-5276 or go to www.
amherstsoccerclub.com.

HIGH SCHOOL

Souhegan openings

Souhegan High School is accepting applications for the following coaching positions for the fall: JV girls volleyball, freshman boys soccer, freshman girls volleyball and freshman field hockey. Interested candidates should send a letter of interest, a resume and three references to the attention of Dick Miller, athletic director, at Souhegan High School.

Milford opening

Milford High School is accepting applications for the following coaching positions for the fall: JV girls soccer. Candidates should complete an application, which can be found at www.milfordk12.org, and click on human resources. Submit the application along with a cover letter, resume and three letters of reference to: Marc Maurais, athletic director, Milford High School, 100 West St. Milford, NH 03055.

Source: http://www.cabinet.com/cabinet/cabinetsports/1010360-308/cabinet-sports-talk.html

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Snake-bot slithers through nuclear power plant in mobility test

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